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FGF-21

CAT: 0209-M10-047-L1000Size: 1000 μgDry Ice: NoHazardous: No
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CAT#:0209-M10-047-L1000Size:1000 μg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FGF-21 is a secreted growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-21, in the presence of β-Klotho as a protein cofactor, signals through the FGFR 1c and 4 receptors, and stimulates insulin-independent glucose uptake by adipocytes. Recombinant Murine FGF-21 is a 20.1 kDa protein containing 182 amino acid residues.
Synonyms
Fibroblast Growth Factor-21, FGFL
NCBI Gene ID
56636
UniProt
Q9JJN1
Accession Number
NP_064397.1
Accession Number mRNA
NM_020013.4
Reactivity
Mouse
Sequence
MAYPIPDSSP LLQFGGQVRQ RYLYTDDDQD TEAHLEIRED GTVVGAAHRS PESLLELKAL KPGVIQILGV KASRFLCQQP DGALYGSPHF DPEACSFREL LLEDGYNVYQ SEAHGLPLRL PQKDSPNQDA TSWGPVRFLP MPGLLHEPQD QAGFLPPEPP DVGSSDPLSM VEPLQGRSPS YAS
Detection Range
Determined by its ability to stimulate the proliferation of murine NIH-3T3 cells.
Endotoxin
< 0.1 ng/μg of protein (< 1 EU/μg)
Purity
≥ 95% by SDS-PAGE gel and HPLC analyses
Length
182
Molecular Weight
20.1 kDa
Formulation
Lyophilized
Host or Source
E. coli
Species
Mouse

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