Quinidine-d3

CAT: 0804-HY-B1751SSize: 2.5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B1751SSize:2.5 mg
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Description
Quinidine-d3 is the deuterium labeled Quinidine. Quinidine is an antiarrhythmic agent for the treatment of abnormal heart rhythms and also malaria.
CAS Number
[1267657-68-0]
UNSPSC
12352005
Hazard Statement
H301-H315
Target
Isotope-Labeled Compounds; Parasite
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Field of Research
Infection; Cardiovascular Disease
Solubility
10 mM in DMSO
Smiles
O[C@H]([C@]1([H])[N@@]2C[C@@H]([C@@H](CC2)C1)C=C)C3=CC=NC4=C3C=C(OC([2H])([2H])[2H])C=C4
Molecular Formula
C20H21D3N2O2
Molecular Weight
327.44
Precautions
P264-P270-P280-P302+P352-P330-P362+P364-P405-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Kehl SJ, et al. Quinidine-induced inhibition of the fast transient outward K+ current in rat melanotrophs. Br J Pharmacol. 1991 Jul;103 (3) :1807-13.|[3]Roden DM, et al. Class I antiarrhythmic agents: quinidine, procainamide and N-acetylprocainamide, disopyramide.|[4]Moody DE, et al. Quinidine inhibits in vivo metabolism of amphetamine in rats: impact upon correlation between GC/MS and immunoassay findings in rat urine. J Anal Toxicol. 1990 Sep-Oct;14 (5) :311-7.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
Plasmodium

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