Products for Research Use Only
RegisterLogin

Quinidine N-oxide

CAT: 0804-HY-130318Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-130318Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Quinidine N-oxide is a pharmacologically inactive metabolite of Quinidine. Quinidine is an active probe of CYP3A4[1].
CAS Number
70116-00-6
UNSPSC
12352005
Target
Cytochrome P450; Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/quinidine-n-oxide.html
Smiles
C=C[C@@H](C[N@+]1([O-])CC2)[C@@H]2C[C@@H]1[C@@H](O)C3=CC=NC4=CC=C(OC)C=C34
Molecular Formula
C20H24N2O3
Molecular Weight
340.42
References & Citations
[1]Damkier P, et al. Quinidine as a probe for CYP3A4 activity: intrasubject variability and lack of correlation with probe-based assays for CYP1A2, CYP2C9, CYP2C19, and CYP2D6. Clin Pharmacol Ther. 2000 Aug;68 (2) :199-209.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

quinidine-N-oxide

major metabolite of quinidine; RN given refers to (9S)-isomer

CAS Number70116-00-6
PubChem CID23622544
IUPAC Name(S)-[(1R,2R,4S,5R)-5-ethenyl-1-oxido-1-azoniabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol
Molecular FormulaC20H24N2O3
Molecular Weight340.4
XLogP2.9
Topological Polar Surface Area60.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count25
Formal Charge0
Complexity501
SMILES
COC1=CC2=C(C=CN=C2C=C1)[C@@H]([C@H]3C[C@@H]4CC[N@+]3(C[C@@H]4C=C)[O-])O
InChI
InChI=1S/C20H24N2O3/c1-3-13-12-22(24)9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(25-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19+,20-,22+/m0/s1
InChIKey
WVDIZKMXQMCCAA-ROCUERRRSA-N
Chemical Structure
2D Structure
2D structure of quinidine-N-oxide
CAS: 70116-00-6
CID: 23622544
Formula: C20H24N2O3
MW: 340.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight340.4
XLogP32.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass340.17869263
Monoisotopic Mass340.17869263
Topological Polar Surface Area60.4 Ų
Heavy Atom Count25
Formal Charge0
Complexity501
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-W740127Quinidine-d3 N-Oxide
HY-B1751H-01Quinidine
HY-144147S-01N-Methyl Quinidine-d3 (iodide)
HY-150123-01Quinidine methiodide
HY-B1751EQuinidine polygalacturonate
HY-B1751AQuinidine (sulfate)
HY-B1751SQuinidine-d3
HY-W127842-01N, N-Dimethyldecylamine N-oxide
HY-W576312N, N-Dimethyltryptamine N-oxide
HY-N15707Isocorydine N-oxide

Alternative Products

CatalogName
288514-01Quinidine N-oxide
TRC-Q685017-1MGQuinidine-d3 N-Oxide
AR-Q01103-01Quinidine N-Oxide Impurity
sc-212615Quinidine 1'-Oxide
TRC-Q685010-1MGQuinidine 1’-Oxide
AR-Q03888-01Quinidine EP Impurity C N-Oxide (Dihydroquinidine N-Oxide)
sc-219689Quinidine-d3 1'-Oxide
AR-Q01101-01N-Methyl Quinidine-d3 Iodide
020393-01Quinidine
90026553+) -Quinidine

Popular Products