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TRAF6 peptide (TFA)

CAT: 0804-HY-P3709A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P3709A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TRAF6 peptide TFA is a specific TRAF6-p62 inhibitor. TRAF6 peptide TFA potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide TFA has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke[1].
UNSPSC
12352209
Target
E1/E2/E3 Enzyme; p62
Type
Peptides
Related Pathways
Autophagy; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/traf6-peptide-tfa.html
Purity
98.20
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N1[C@@H](CCC1)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N2[C@@H](CCC2)C(N[C@@H](CCC(O)=O)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CO)C(NCC(N3[C@@H](CCC3)C(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N4[C@@H](CCC4)C(N[C@@H](CO)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N.O=C(O)C(F)(F)F
Molecular Formula
C145H238N34O44.xC2HF3O2
Molecular Weight
3161.64 (free acid)
References & Citations
[1]Wooten, Marie W. Substances interfering with TRAF6-p62 interaction for inhibiting intracellular aggregate formation and methods for screening for such substances. Patent WO2005050170A2.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported

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