MANS peptide (TFA)

CAT: 0804-HY-P10218A-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P10218A-01Size:5 mg
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Description
MANS peptide TFA is the TFA salt form of MANS peptide (HY-P10218) . MANS peptide TFA is an inhibitor for myristoylated alanine-rich C kinase substrate (MARCKS), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis[1].
UNSPSC
12352209
Target
MARCKS; PKC
Type
Peptides
Related Pathways
Cytoskeleton; Epigenetics; TGF-beta/Smad
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mans-peptide-tfa.html
Purity
99.88
Solubility
DMSO : 13.3 mg/mL (ultrasonic)
Smiles
CCCCCCCCCCCCCC(NCC(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.O=C(C(F)(F)F)O.[x]
Molecular Formula
C111H184N30O35.xC2HF3O2
Molecular Weight
2498.83 (free acid)
References & Citations
[1]Chen CH, et al., A peptide that inhibits function of Myristoylated Alanine-Rich C Kinase Substrate (MARCKS) reduces lung cancer metastasis. Oncogene. 2014 Jul 10;33 (28) :3696-706.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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