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CCP peptide (TFA)

CAT: 0804-HY-P2171A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P2171A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CCP peptide TFA is a synthetic cyclic citrullinated peptide (CCP) and used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide TFA functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA) [1][2].
UNSPSC
12352209
Target
Others
Type
Peptides
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ccp-peptide-tfa.html
Purity
96.64
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(N[C@H]1CC2=CN=CN2)[C@@H](NC([C@@H](NC([C@H](CC3=CN=CN3)N)=O)CCC(N)=O)=O)CSSC[C@@H](C(NCC(N[C@H](C(N[C@H](C(NCC(N[C@H](C(O)=O)CO)=O)=O)CO)=O)CCCNC(N)=N)=O)=O)NC([C@H](CCCNC(N)=N)NC(CNC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@H](CCCNC(N)=N)NC(CNC([C@H](CCCNC(N)=O)NC([C@]([H])([C@@H](C)O)NC([C@H](CO)NC([C@H](CCC(O)=O)NC([C@H](CCC(N)=O)NC1=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
Molecular Formula
C89H146N41F3O34S2
Molecular Weight
2455.49
References & Citations
[1] Puszczewicz M, et al. Role of anti-citrullinated protein antibodies in diagnosis and prognosis of rheumatoid arthritis. Arch Med Sci. 2011 Apr;7 (2) :189-94.|[2]Söderlin MK, et al. Antibodies against cyclic citrullinated peptide (CCP) and levels of cartilage oligomeric matrix protein (COMP) in very early arthritis: relation to diagnosis and disease activity. Scand J Rheumatol. 2004;33 (3) :185-8.|[3]Schellekens GA, et al. The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide. Arthritis Rheum. 2000 Jan;43 (1) :155-63.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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