TRAF6 peptide

• UNSPSC Description:

  TRAF6 peptide is a specific TRAF6-p62 inhibitor. TRAF6 peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke[1].

• Target Antigen:

  E1/E2/E3 Enzyme; p62

• Type:

  Peptides

• Related Pathways:

  Autophagy;Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/traf6-peptide.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@H]1N(CCC1)C(CNC([C@H](CO)NC([C@H](C)NC([C@H](CO)NC([C@H](CCC(O)=O)NC([C@H]2N(CCC2)C([C@H](C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](C(C)C)NC([C@H](C)NC([C@H]3N(CCC3)C([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](C(C)C)NC([C@H](C)NC([C@@H](N)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N4[C@@H](CCC4)C(N[C@@H](CO)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)CCCCN)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)=O

• Molecular Weight:

  3161.64

• References & Citations:

  [1]Wooten, Marie W. Substances interfering with TRAF6-p62 interaction for inhibiting intracellular aggregate formation and methods for screening for such substances. Patent WO2005050170A2.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  852805-92-6