TRAF6 peptide

TRAF6 peptide

• CAS Number: 852805-92-6
• UNSPSC Description: TRAF6 peptide is a specific TRAF6-p62 inhibitor. TRAF6 peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke[1].
• Target Antigen: E1/E2/E3 Enzyme; p62
• Type: Peptides
• Related Pathways: Autophagy;Metabolic Enzyme/Protease
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/traf6-peptide.html
• Solubility: 10 mM in DMSO
• Smiles: O=C([C@H]1N(CCC1)C(CNC([C@H](CO)NC([C@H](C)NC([C@H](CO)NC([C@H](CCC(O)=O)NC([C@H]2N(CCC2)C([C@H](C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](C(C)C)NC([C@H](C)NC([C@H]3N(CCC3)C([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](C(C)C)NC([C@H](C)NC([C@@H](N)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N4[C@@H](CCC4)C(N[C@@H](CO)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)CCCCN)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)=O
• Molecular Weight: 3161.64
• References & Citations: [1]Wooten, Marie W. Substances interfering with TRAF6-p62 interaction for inhibiting intracellular aggregate formation and methods for screening for such substances. Patent WO2005050170A2.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported