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TRAF6 peptide

CAT: 0804-HY-P3709Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P3709Size:1 Each
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Description
TRAF6 peptide is a specific TRAF6-p62 inhibitor. TRAF6 peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke[1].
CAS Number
852805-92-6
UNSPSC
12352209
Target
E1/E2/E3 Enzyme; p62
Type
Peptides
Related Pathways
Autophagy; Metabolic Enzyme/Protease
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/traf6-peptide.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1N(CCC1)C(CNC([C@H](CO)NC([C@H](C)NC([C@H](CO)NC([C@H](CCC(O)=O)NC([C@H]2N(CCC2)C([C@H](C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](C(C)C)NC([C@H](C)NC([C@H]3N(CCC3)C([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](C(C)C)NC([C@H](C)NC([C@@H](N)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N4[C@@H](CCC4)C(N[C@@H](CO)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)CCCCN)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C145H238N34O44
Molecular Weight
3161.64
References & Citations
[1]Wooten, Marie W. Substances interfering with TRAF6-p62 interaction for inhibiting intracellular aggregate formation and methods for screening for such substances. Patent WO2005050170A2.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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