A666 peptide (TFA)

• Description:

  A666 peptide TFA is a highly selective prestin ligand. A666 peptide TFA enables active drug delivery (e.g., dexamethasone) to outer hair cells (OHCs) . A666 peptide TFA is promising for research of cisplatin-induced ototoxicity protection and sensorineural hearing loss interventions[1].

• UNSPSC:

  12352209

• Target:

  Others

• Related Pathways:

  Others

• Field of Research:

  Cancer

• Purity:

  97.60

• Smiles:

  O=C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(NCC(N[C@@H](CC4=CC=CC=C4)C(NCC(N[C@@H](CC5=CNC6=CC=CC=C56)C(N[C@@H](CC7=CNC8=CC=CC=C78)C(N[C@@H](CC(C)C)C(N[C@@H](CC9=CNC=N9)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CS)N.OC(C(F)(F)F)=O.[x]

• Molecular Formula:

  C83H107N21O16S.xC2HF3O2

• Molecular Weight:

  1686.93 (free base)

• References & Citations:

  [1]Wang X, et al. A666-conjugated nanoparticles target prestin of outer hair cells preventing cisplatin-induced hearing loss. Int J Nanomedicine. 2018 Nov 14;13:7517-7531.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported