BACE1-IN-1

CAT: 0804-HY-100182-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-100182-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively.
CAS Number
[1310347-50-2]
UNSPSC
12352005
Target
Beta-secretase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/BACE1-IN-1.html
Purity
98.72
Solubility
DMSO : 85 mg/mL (ultrasonic)
Smiles
O=C(C1=NC=C(C#N)C=C1)NC2=CC=C(F)C([C@@]3(C)N=C(N)OCC3(F)F)=C2
Molecular Formula
C18H14F3N5O2
Molecular Weight
389.33
References & Citations
[1]Hilpert H, et al. β-Secretase (BACE1) inhibitors with high in vivo efficacy suitable for clinical evaluation in Alzheimer's disease. J Med Chem. 2013 May 23;56 (10) :3980-95.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
BACE1

Related Products

CatalogName
HY-147758BACE1/2-IN-1
HY-151260AChE/BACE1/GSK3β-IN-1
HY-144741BACE1-IN-9
HY-128594BACE1-IN-4
HY-130244BACE1-IN-5
HY-151348BACE1-IN-11
HY-161359BACE1-IN-14
HY-145345BACE1-IN-6
HY-173226BACE1-IN-15
HY-P3426BACE1-IN-10

Alternative Products

CatalogName
MBS5766121BACE1-IN-1
MBS5804648BACE1/2-IN-1
A12183-10BACE1-IN-1 10mg
A12183-50BACE1-IN-1 50mg
BZ0210-2PcDNA3.1-BACE1
A12183-5BACE1-IN-1 5mg
A12183-25BACE1-IN-1 25mg
A12183-100BACE1-IN-1 100mg
A12183-1BACE1-IN-1 1mg
048364BACE1 (Genentech BACE1) discontinued

Popular Products