Products for Research Use Only

BACE1/2-IN-1

CAT: 0931-T61956-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T61956-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2671036-34-1
Target
Beta Amyloid, Beta-Secretase, Others
Related Pathways
Neuroscience, Others
Bioactivity
BACE1/2-IN-1 (compound 34) is an effective BACE1 and BACE2 inhibitor with IC50 values of 0.01 and 0.0053 μM, respectively. It exhibits a lower Pgp efflux ratio, improved passive permeability, and decreased metabolic stability in liver microsomes.
Smiles
C(OC[C@H]1[C@H](C)C1)(C)(C)[C@H]2[C@]([C@@]34[C@@](CN(C3)C=5N=CC=CN5)(CSC(N)=N4)[H])(C2)[H]
Molecular Formula
C21H31N5OS
Molecular Weight
401.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C