4β-Hydroxycholesterol

• Description:

  4β-hydroxy Cholesterol is a major oxysterol cholesterol metabolite and a precursor in the synthesis of bile acids that is found in human circulation[1].

• UNSPSC:

  12352211

• Target:

  Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/4β-hydroxycholesterol.html

• Purity:

  99.96

• Solubility:

  DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : 16.67 mg/mL (ultrasonic)

• Smiles:

  O[C@@H] (CC[C@]1 (C2=CC[C@@]3 ([C@@]1 (CC[C@]4 ([C@]3 (CC[C@@]4 ([C@@H] (CCCC (C) C) C) [H]) [H]) C) [H]) [H]) C) [C@@H]2O

• Molecular Formula:

  C27H46O2

• Molecular Weight:

  402.65

• References & Citations:

  [1]Granchi C, Rizzolio F, Bordoni V, Caligiuri I, Manera C, Macchia M, Minutolo F, Martinelli A, Giordano A, Tuccinardi T. 4-Aryliden-2-methyloxazol-5 (4H) -one as a new scaffold for selective reversible MAGL inhibitors. J Enzyme Inhib Med Chem. 2016;31 (1) :137-46.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  17320-10-4