Products for Research Use Only
RegisterLogin

25-Hydroxycholesterol-d6

CAT: 0804-HY-113134SSize: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-113134SSize:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
25-Hydroxycholesterol-d6 (25-OHC-d6) is the deuterium labeled 25-Hydroxycholesterol. 25-Hydroxycholesterol is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC50≈65 nM) and selective suppressor of IgA production by B cells[1][2].
CAS Number
88247-69-2
Product Name Alternative
25-OHC-d6
UNSPSC
12352211
Hazard Statement
H225, H301+H311+H331, H370
Target
Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Inflammation/Immunology
Purity
99.0
Solubility
Ethanol : 14.29 mg/mL (ultrasonic; warming)
Smiles
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C([2H])([2H])[2H])(O)C([2H])([2H])[2H])([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=CC3)C
Molecular Formula
C27H40D6O2
Molecular Weight
408.69
Precautions
H225, H301+H311+H331, H370
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]McDonald JG, et al. Editorial: 25-Hydroxycholesterol: a new life in immunology. J Leukoc Biol. 2010 Dec;88 (6) :1071-2.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-113134-0125-Hydroxycholesterol
HY-N15915Ent-25-Hydroxycholesterol
HY-113134R-0125-Hydroxycholesterol (Standard)
HY-1339747-keto-25-Hydroxycholesterol
HY-N1587722-NBD 25-Hydroxycholesterol
HY-15328-0125-Hydroxy VD2-d6
HY-113962S-017α,25-Dihydroxycholesterol-d6
HY-N2370-0124-Hydroxycholesterol
HY-N2371-0127-Hydroxycholesterol
HY-124265-014β-Hydroxycholesterol

Alternative Products

CatalogName
TRC-H917972-75MG26-Hydroxycholesterol-d6
H1030017-alpha-Hydroxycholesterol-d6
BUP06234-0125-Hydroxycholesterol
TRC-H772781-5MG7-beta-Hydroxycholesterol-D6
GTR10399457Mouse 25-hydroxycholesterol
GTR10419253Rabbit 25-hydroxycholesterol
TYD-04074-01Ent-25-Hydroxycholesterol
GTR10437159Canine 25-hydroxycholesterol
GTR10396720Goat 25-hydroxycholesterol

Popular Products