25-Hydroxycholesterol (Standard)

• Description:

  25-Hydroxycholesterol (Standard) is the analytical standard of 25-Hydroxycholesterol. This product is intended for research and analytical applications. 25-Hydroxycholesterol (25-OHC) is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC50≈65 nM) and selective suppressor of IgA production by B cells.

• UNSPSC:

  12352100

• Target:

  Endogenous Metabolite; Reference Standards

• Related Pathways:

  Metabolic Enzyme/Protease; Others

• Field of Research:

  Inflammation/Immunology

• Smiles:

  CC(C)(O)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C

• Molecular Formula:

  C27H46O2

• Molecular Weight:

  402.65

• References & Citations:

  [1]McDonald JG, et al. Editorial: 25-Hydroxycholesterol: a new life in immunology. J Leukoc Biol. 2010 Dec;88 (6) :1071-2.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [2140-46-7]