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ISIS 449884

CAT: 0804-HY-159696Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-159696Size:1 Each
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Description
ISIS 449884 is a 2'-O-methoxyethyl antisense oligonucleotide that targets GCGR. ISIS 449884 has an ability to reduce hepatic glucose output and lower the blood glucose level. ISIS 449884 can be used for the study of type 2 diabetes mellitus (T2DM) [1].
CAS Number
1428588-67-3
UNSPSC
12352208
Target
GCGR
Type
Oligonucleotides
Related Pathways
GPCR/G Protein
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/isis-449884.html
Smiles
[ISIS449884]
References & Citations
[1]Linong Ji, et al. ISIS 449884 Injection Add-On to Metformin in Patients with Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Phase II Clinical Study. Diabetes Ther. 2024 Oct;15 (10) :2183-2196.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

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