ISIS 14803

• Description:

  ISIS 14803 is a 20-unit antisense phosphorothioate oligodeoxynucleotide that binds to hepatitis C virus (HCV) RNA at the translation initiation region of the internal ribosome entry site (IRES) and inhibits protein expression in cell culture.

• UNSPSC:

  12352208

• Target:

  HCV

• Type:

  Oligonucleotides

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/isis-14803.html

• Solubility:

  10 mM in H2O

• Smiles:

  [ISIS14803]

• References & Citations:

  [1]McHutchison JG, Patel K, Pockros P, et al. A phase I trial of an antisense inhibitor of hepatitis C virus (ISIS 14803), administered to chronic hepatitis C patients. J Hepatol. 2006;44 (1) :88-96. doi:10.1016/j.jhep.2005.09.009

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Oligonucleotides

• Clinical Information:

  Phase 2

• CAS Number:

  [223603-41-6]