ISIS 2503

• Description :

  ISIS-2503 is a 20-mer antisense oligonucleotide that inhibits Ha-Ras expression

• UNSPSC :

  12352208

• Target :

  Ras

• Type :

  Oligonucleotides

• Related Pathways :

  GPCR/G Protein; MAPK/ERK Pathway

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/isis-2503.html

• Solubility :

  10 mM in H2O

• Smiles :

  [ISIS2503]

• References & Citations :

  [1]Adjei AA, Dy GK, Erlichman C, et al. A phase I trial of ISIS 2503, an antisense inhibitor of H-ras, in combination with gemcitabine in patients with advanced cancer. Clin Cancer Res. 2003;9 (1) :115-123.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Oligonucleotides

• Clinical Information :

  Phase 2

• CAS Number :

  [149957-14-2]