ISIS 416858

CAT: 0804-HY-134005Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-134005Size:1 Each
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Description
ISIS 416858, a single-stranded antisense oligodeoxynucleotide, is a potent and selective inhibitor of FXI mRNA expression.
CAS Number
[1223657-78-0]
UNSPSC
12352100
Target
Factor XI
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/isis-416858.html
Solubility
10 mM in H2O
Smiles
[ISIS416858]
References & Citations
[1]Younis HS, Crosby J, Huh JI, et al. Antisense inhibition of coagulation factor XI prolongs APTT without increased bleeding risk in cynomolgus monkeys. Blood. 2012;119 (10) :2401-2408. doi:10.1182/blood-2011-10-387134
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 2

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