BPH-715

• Product Name Alternative:

  Tyrosine kinase-IN-1

• UNSPSC Description:

  BPH-715 is a bisphosphonate, inhibits Plasmodium liver-stage growth, with an IC50 of 10 μM for Plasmodium exoerythrocytic forms in HepG2 cells[1].

• Target Antigen:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/BPH-715.html

• Purity:

  99.62

• Solubility:

  0.5 M NaOH : 80 mg/mL (ultrasonic;adjust pH to 11 with NaOH)|DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  CCCCCCCCCCOC1=C[N+](CC(P(O)(O)=O)P(O)([O-])=O)=CC=C1

• Molecular Weight:

  423.38

• References & Citations:

  [1]Singh AP, et al. Lipophilic bisphosphonates are potent inhibitors of Plasmodium liver-stage growth. Antimicrob Agents Chemother. 2010 Jul;54(7):2987-93.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1059677-23-4