WJM-715

• Description :

  WJM-715 is an antimalarial agent with an EC50 of 0.015 μM by trageting STAR-related lipid transfer protein (PfSTART1) with a KD of 14 nM[1].

• UNSPSC :

  12352005

• Target :

  Parasite

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/wjm-715.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=S(N1CCOCC1)(C2=C(Cl)C=CC(NC(C)(C)C(NC3=CN=CC(Cl)=C3)=O)=C2)=O

• Molecular Formula :

  C19H22Cl2N4O4S

• Molecular Weight :

  473.37

• References & Citations :

  [1]Nguyen W, et al., Activity refinement of aryl amino acetamides that target the P. falciparum STAR-related lipid transfer 1 protein. Eur J Med Chem. 2024 Mar 25;270:116354.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported