BPH-652

• Description:

  BPH-652 is a S. aureus dehydrosqualene synthase (CrtM) inhibitor, with a Ki of 1.5 nM and an IC50 of 100-300 nM (S. aureus pigment formation) [1].

• UNSPSC:

  12352005

• Target:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/bph-652.html

• Purity:

  98.97

• Solubility:

  H2O : 25 mg/mL (ultrasonic)

• Smiles:

  O=S(C(P(O[K])(O[K])=O)CCCC1=CC=CC(OC2=CC=CC=C2)=C1)(O[K])=O

• Molecular Formula:

  C16H16K3O7PS

• Molecular Weight:

  500.63

• References & Citations:

  [1]Liu CI, et al. A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science. 2008 Mar 7;319 (5868) :1391-4.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  157124-84-0