BMS 310705

• Description :

  BMS 310705 (21-Aminoepothilone B) is an analog of Epothilone B (HY-17029), targeting to malignancies such as ovarian, renal, bladder, and lung carcinoma. BMS 310705 induces significant apoptosis via mitochondrial-mediated pathway[1].

• Product Name Alternative :

  21-Aminoepothilone B

• UNSPSC :

  12352005

• Target :

  Apoptosis

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/bms-310705.html

• Purity :

  99.10

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  C[C@@]12[C@H](C[C@H](OC(C[C@@H](C(C)(C)C([C@H](C)[C@@H](O)[C@@H](C)CCC2)=O)O)=O)/C(C)=C/C3=CSC(CN)=N3)O1

• Molecular Formula :

  C27H42N2O6S

• Molecular Weight :

  522.70

• References & Citations :

  [1]Uyar D, et al. Apoptotic pathways of epothilone BMS 310705. Gynecol Oncol. 2003 Oct;91 (1) :173-8.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [280578-49-6]