BMS 310705

• Description:

  BMS 310705 (21-Aminoepothilone B) is an analog of Epothilone B (HY-17029), targeting to malignancies such as ovarian, renal, bladder, and lung carcinoma. BMS 310705 induces significant apoptosis via mitochondrial-mediated pathway[1].

• Product Name Alternative:

  21-Aminoepothilone B

• UNSPSC:

  12352005

• Target:

  Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/bms-310705.html

• Purity:

  99.10

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  C[C@@]12[C@H](C[C@H](OC(C[C@@H](C(C)(C)C([C@H](C)[C@@H](O)[C@@H](C)CCC2)=O)O)=O)/C(C)=C/C3=CSC(CN)=N3)O1

• Molecular Formula:

  C27H42N2O6S

• Molecular Weight:

  522.70

• References & Citations:

  [1]Uyar D, et al. Apoptotic pathways of epothilone BMS 310705. Gynecol Oncol. 2003 Oct;91 (1) :173-8.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  280578-49-6