MG-002

CAT: 0013-GTR19274855-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19274855-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

MG-002 is an orally active eIF4A inhibitor. It suppresses mRNA translation by non-productively clamping eukaryotic translation initiation factor 4A (eIF4A) onto RNA, thereby hindering ribosome recruitment and scanning. MG-002 selectively inhibits the growth and metastasis of triple-negative breast cancer (TNBC) tumors and induces apoptosis. It also significantly reduces the expression of c-MYC and cyclin D1 proteins. MG-002 is useful for TNBC research.

CAS Number

3076503-34-6

Smiles

O[C@]12[C@] ([C@@H] ([C@@H] (C (NOC) =O) [C@H]1O) C3=CC=CC=C3) (OC=4C2=C (OC) N=C (OC) C4) C5=CC=C (C#N) C=C5

Molecular Formula

C27H25N3O7

Molecular Weight

503.51

Storage Conditions

-20°C

Notes

For research use only.

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MG-002

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