CB-002

CAT: 0013-GTR19154144Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19154144Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

CB-002 is a novel small molecule that restores p53 function in mutant p53-expressing colorectal cancer cells without toxicity to normal human fibroblasts; increases expression of endogenous p53 target genes NOXA, DR5, and p21 and cell death; decreases the stability of mutant p53 in RXF393 cancer cells and an exogenously expressed R175H p53 mutant in HCT116 p53-null cells.

CAS Number

61034-15-9

Purity

>98%

Smiles

N1C2=C (N (C) C (=O) N (C) C2=O) N=C1NC1=CC=CC=C1

Molecular Formula

C13H13N5O2

Molecular Weight

271.28

Notes

For research use only.

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