I3IN-002

CAT: 0013-GTR19264368-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19264368-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

I3IN-002 is a small molecule inhibitor targeting the RNA-binding protein IGF2BP3, with an IC50 value of approximately 2 μM in SEM cells. It disrupts the interaction with m6A-modified mRNA, destabilizing target genes (such as CDK6, MYC, and BCL2), thereby inhibiting the growth of leukemia cells, inducing cell cycle arrest, and promoting apoptosis. I3IN-002 shows potential for research in B-cell acute lymphoblastic leukemia.

CAS Number

552829-57-9

Field of Research

Cell Biology, Signal Transduction

Smiles

O=C (NC=1C=CC=CC1C (F) (F) F) CSC=2N=NC3=C (N2) NC4=CC=C (C=C34) CC

Molecular Formula

C20H16F3N5OS

Molecular Weight

431.43

Storage Conditions

-20°C

Notes

For research use only.

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I3IN-002

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