STAT3/NF-κB-IN-1

CAT: 0013-GTR19263792-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19263792-01Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

STAT3/NF-κB-IN-1 is a potent inhibitor of STAT3 and NF-κB, exhibiting IC50 values of 5.86 μM for STAT3 and 4.22 μM for NF-κB in 4 T1 cells. It induces apoptosis by upregulating key apoptotic regulators (caspases-3, 9, Bax) and downregulating Bcl-2 expression. STAT3/NF-κB-IN-1 shows significant anticancer activity against breast cancer cell lines and can reduce tumor volume in vivo. It is applicable for research in breast cancer.

Field of Research

Cancer Biology, Cell Biology, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology

Storage Conditions

-20°C

Notes

For research use only.

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