NF-κB-IN-1

CAT: 0013-GTR19165800-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19165800-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

NF-κB-IN-1 is a synthetic 4-arylidene curcumin analog that acts as a potent inhibitor of the NF-κB signaling pathway by directly targeting IKK. This compound has demonstrated efficacy in vitro by reducing the viability and clonogenic growth of lung cancer cells such as A549.

CAS Number

1227098-15-8

Product Name Alternative

Crucumin, A549, 4-arylidene, 1,6-Heptadiene-3,5-dione, 1,7-bis (3,4-dimethoxyphenyl) -4-[ (4-hydroxy-3-methoxyphenyl) methylene]-, (1E,6E) -, cancer, I kappa B kinase, IκB kinase, IκB, inhibit, IkB, IkB/IKK, IKK, Inhibitor, NFκBIN1, NF-κB-IN-1, NF-κB, NFκB, NF-kB-IN-1, NFkB, NF-kB, NF κB IN 1, NF-kappaB-IN-1, pathway, signaling

Field of Research

Signal Transduction

Purity

99.03% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.77 mM) ; DMSO:40 mg/mL (75.39 mM)

Smiles

COc1ccc (\C=C\C (=O) C (=Cc2ccc (O) c (OC) c2) C (=O) \C=C\c2ccc (OC) c (OC) c2) cc1OC

Molecular Formula

C31H30O8

Molecular Weight

530.57

Storage Conditions

-20°C

Notes

For research use only.

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Catalog	Name
BA8604-1	NF-κB-IN-1
BUP07719-01	NF-?B-IN-1
T203058-01	TLR4/NF-κB-IN-1
T210896-01	NF-κB degrader 1
HY-175227	STAT3/NF-κB-IN-1
HY-146058	NF-κB/PON1-IN-1
T63119-01	NF-κB/MAPK-IN-1
BUP05080-01	NF-?B/MAPK-IN-1
T207236-01	NF-κB/HIF-1α-IN-1
HY-147836	Akt/NF-κB/JNK-IN-1

NF-κB-IN-1

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