Products for Research Use Only
RegisterLogin

HDAC-IN-91

CAT: 0013-GTR19263745-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19263745-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
HDAC-IN-91 is a multi-target inhibitor affecting HDAC [HDAC1 (IC50= 134.22 nM), HDAC2 (IC50= 66.29 nM) ], carbonic anhydrase [CA IX (KI= 72.03 nM), XII (KI= 50.76 nM) ], and tubulin polymerization (IC50= 2.56 μM) . It inhibits PARP1 and increases the Bax/Bcl-2 ratio. The compound causes cell cycle arrest at the G2/M phase and triggers apoptosis through mitochondrial pathways. By inhibiting tubulin polymerization, HDAC-IN-91 exhibits potent cytotoxic activity. This compound is applicable in research on breast cancer, colorectal cancer, cervical cancer, and lung cancer.
Field of Research
Cell Biology, Epigenetics & Chromatin, Metabolism Research, Molecular Biology, Protein Biochemistry, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19264224-01α-Glucosidase-IN-91
GTR19261259-01EGFR-IN-91
GTR19220932-01HDAC-IN-53
GTR19218839-01HDAC-IN-58
GTR19212332-01HDAC-IN-50
GTR19211793-01HDAC-IN-52
GTR19205665-01HDAC-IN-4
GTR19188298-01HDAC-IN-40
GTR19187309-01HDAC-IN-32
GTR19185950-01HDAC-IN-41

Alternative Products

CatalogName
T211349-01HDAC-IN-91
HY-161688HDAC-IN-73
HY-161984HDAC-IN-76
HY-149370HDAC-IN-60
HY-142965HDAC-IN-28
HY-147892HDAC-IN-42
HY-162487HDAC-IN-72
HY-147966HDAC-IN-43
HY-18362HDAC-IN-5
HY-150597HDAC-IN-46

Popular Products