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HDAC-IN-50

CAT: 0013-GTR19212332-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19212332-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HDAC-IN-50 is a potent, orally bioavailable dual inhibitor of FGFR and HDAC enzymes, demonstrating low nanomolar IC50 values. It exhibits anti-tumor activity by inducing apoptosis and G0/G1 cell cycle arrest, concurrently reducing levels of pFGFR1, pERK, and pSTAT3 in cellular models. This profile supports its investigation in oncology research, particularly for cancers driven by FGFR signaling and epigenetic dysregulation.
CAS Number
2653339-26-3
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Smiles
N (CCNC (C) C) (C1=CC2=C (C=C1) N=CC (=N2) C3=CN (CCCCCCC (NO) =O) N=C3) C4=CC (OC) =CC (OC) =C4
Molecular Formula
C31H41N7O4
Molecular Weight
575.7
Storage Conditions
-20°C
Notes
For research use only.

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