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EGFR-IN-91

CAT: 0013-GTR19261259-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19261259-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-91 (compound 9) is an orally active EGFR inhibitor capable of crossing the blood-brain barrier. It effectively inhibits EGFRL858R/C797S and EGFRexon 19del/C797S, leading to tumor regression in patient-derived xenograft (PDX) mouse models. EGFR-IN-91 shows potential for inhibiting locally advanced and metastatic non-small cell lung cancer (NSCLC) driven by EGFR mutations.
CAS Number
3032113-20-2
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
FC=1C (Cl) =CC=CC1NC=2N=CN=C3C=C (OC) C (OCCON4CCN (C) CC4) =CC32
Molecular Formula
C22H25ClFN5O3
Molecular Weight
461.92
Storage Conditions
-20°C
Notes
For research use only.

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