Products for Research Use Only
RegisterLogin

STING Degrader-2

CAT: 0013-GTR19263243-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19263243-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
STINGDegrader-2 (Compound SI-43) is an inhibitor and mutant-specific degrader of STING. It effectively suppresses cGAMP-induced STING activation and significantly reduces the release of IFN-β and CXCL-10. By binding to two pockets of the STING dimer, it inhibits activity and induces proteasome-independent degradation of the mutant STINGS154 and STINGM155 (DC50 values of 0.31 and 0.76 μM, respectively) . STINGDegrader-2 is applicable in the study of STING-related autoimmune diseases.
Field of Research
Cell Biology, Immunology & Inflammation
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19260346-01STING Degrader 1
GTR19258238-01PROTAC STING degrader-3
GTR19220819PROTAC STING Degrader-1
GTR19257625-01PROTAC STING degrader-4
GTR19166916-01STING-IN-2
GTR19240430-01STING ligand-2
GTR19236387-01BRD9 Degrader-2
GTR19265324-01ALK degrader 2
GTR19262928-01HuR degrader 2
GTR19220597-01ITK degrader 2

Alternative Products

CatalogName
HY-174136STING Degrader-2
TBI5001-5MGSTING Degrader 1, STING degrader
HY-158036PROTAC STING Degrader-2
abx283593-01STING Degrader 1
HY-162331STING Degrader-1
8053/5STING Degrader SP23
HY-176180PROTAC STING degrader-4
MBS5816830PROTAC STING Degrader-1
HY-173414-01PROTAC STING degrader-3
8054/5STING Degrader N-Me-SP23

Popular Products