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HuR degrader 2

CAT: 0013-GTR19262928-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262928-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HuRdegrader 2 (Compound 3) is a molecular glue that targets and degrades the RNA-binding protein Hu antigen R (HuR), achieving 30% degradation at 0.1 μM. It inhibits the proliferation of Colo-205 cancer cells with an IC50 of ≤200 nM. HuRdegrader 2 also shows high affinity for cereblon with an HTRF ratio < 0.02.
CAS Number
3040301-46-7
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C1NC (=O) C (C2=COC=3C=C (C=CC32) C=4C=CN=C5NC=CC54) CC1
Molecular Formula
C20H15N3O3
Molecular Weight
345.35
Storage Conditions
-20°C
Notes
For research use only.

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