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PROTAC CDK9 degrader-9

CAT: 0804-HY-168518-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-168518-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC CDK9 degrader-9 (compound 29) is a highly selective and efficient CDK9 degrader based on PROTAC technology. PROTAC CDK9 degrader-9 can be used in anti-cancer research[1].
UNSPSC
12352005
Target
CDK; PROTACs
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-cdk9-degrader-9.html
Purity
99.25
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1N(C2CCC(NC2=O)=O)C(C3=C1C=C(F)C(N(CC4)CCN4C5CCN(C(NC6=CC=C(CNC7=NC(N[C@H](CO)CC)=NC8=C(C(C)C)C=NN87)C=C6)=O)CC5)=C3)=O
Molecular Formula
C42H51FN12O6
Molecular Weight
838.93
References & Citations
[1]Nie HJ, et al. Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer. Bioorg Chem. 2024 Oct 9;153:107876.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK9

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