PROTAC CDK9 degrader-9

PROTAC CDK9 degrader-9

• UNSPSC Description: PROTAC CDK9 degrader-9 (compound 29) is a highly selective and efficient CDK9 degrader based on PROTAC technology. PROTAC CDK9 degrader-9 can be used in anti-cancer research[1].
• Target Antigen: CDK; PROTACs
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-cdk9-degrader-9.html
• Smiles: O=C1N(C2CCC(NC2=O)=O)C(C3=C1C=C(F)C(N(CC4)CCN4C5CCN(C(NC6=CC=C(CNC7=NC(N[C@H](CO)CC)=NC8=C(C(C)C)C=NN87)C=C6)=O)CC5)=C3)=O
• Molecular Weight: 838.93
• References & Citations: [1]Nie HJ,et al. Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer. Bioorg Chem. 2024 Oct 9;153:107876.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported