PROTAC CDK9 degrader-9

• UNSPSC Description:

  PROTAC CDK9 degrader-9 (compound 29) is a highly selective and efficient CDK9 degrader based on PROTAC technology. PROTAC CDK9 degrader-9 can be used in anti-cancer research[1].

• Target Antigen:

  CDK; PROTACs

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-cdk9-degrader-9.html

• Smiles:

  O=C1N(C2CCC(NC2=O)=O)C(C3=C1C=C(F)C(N(CC4)CCN4C5CCN(C(NC6=CC=C(CNC7=NC(N[C@H](CO)CC)=NC8=C(C(C)C)C=NN87)C=C6)=O)CC5)=C3)=O

• Molecular Weight:

  838.93

• References & Citations:

  [1]Nie HJ,et al. Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer. Bioorg Chem. 2024 Oct 9;153:107876.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported