NF-κB-IN-14

CAT: 0013-GTR19261968-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19261968-01Size:50 mg

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Description

NF-κB-IN-14 (compound 5e) inhibits nitric oxide production in macrophages induced by LPS, with an IC50 of 6.4 μM. It disrupts the interaction between TLR4 and MyD88 proteins, thereby inhibiting the NF-κB signaling pathway. Additionally, NF-κB-IN-14 reduces ear edema and inflammation in a mouse model of atopic dermatitis.

CAS Number

3019972-01-8

Field of Research

Immunology & Inflammation, Signal Transduction

Smiles

C (/C=C/C1=CC=C (C) C=C1) N2C=3C (N=C2) =C (Cl) N=C (Cl) N3

Molecular Formula

C15H12Cl2N4

Molecular Weight

319.19

Storage Conditions

-20°C

Notes

For research use only.

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NF-κB-IN-14

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