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MTX-216

CAT: 0013-GTR19258650-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258650-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MTX-216 is an ATP-competitive inhibitor targeting both PI3K and EGFR. It simultaneously inhibits Ki-67 and ribosomal S6 phosphorylation, inducing apoptosis in NF1LOF cells. Additionally, MTX-216 suppresses SYK kinase activity with an IC50 of 281 nM. This compound is applicable for melanoma research.
CAS Number
1952236-19-9
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
N#CC=1C=NC2=CC=C (C=C2C1NC3=CC=C (F) C (Cl) =C3) C=4C=NC (Cl) =C (C4) NS (=O) (=O) C
Molecular Formula
C22H14Cl2FN5O2S
Molecular Weight
502.348
Storage Conditions
-20°C
Notes
For research use only.

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