Products for Research Use Only
RegisterLogin

MTX-531

CAT: 0013-GTR19233789-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19233789-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MTX-531 is a dual inhibitor of EGFR and PI3K isoforms with IC50 values in the nanomolar range, and it also exhibits weak PPARγ agonist activity. This compound is a useful research tool for investigating oncogenic signaling pathways in cancer models, both in cellular and animal studies.
CAS Number
2791417-66-6
Field of Research
Cardiovascular Research, Metabolism Research, Molecular Biology, Signal Transduction
Smiles
N ([C@H] (C) C1=CC=CC=C1) C=2C3=C (C=CC (=C3) C=4C=C (NS (C) (=O) =O) C (Cl) =NC4) N=CN2
Molecular Formula
C22H20ClN5O2S
Molecular Weight
453.94
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-[(5P)-2-chloro-5-(4-{[(1R)-1-phenylethyl]amino}quinazolin-6-yl)pyridin-3-yl]methanesulfonamide
CAS Number2791417-66-6
PubChem CID164809124
IUPAC NameN-[2-chloro-5-[4-[[(1R)-1-phenylethyl]amino]quinazolin-6-yl]-3-pyridinyl]methanesulfonamide
Molecular FormulaC22H20ClN5O2S
Molecular Weight453.9
XLogP4.2
Topological Polar Surface Area105
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Heavy Atom Count31
Formal Charge0
Complexity684
SMILES
C[C@H](C1=CC=CC=C1)NC2=NC=NC3=C2C=C(C=C3)C4=CC(=C(N=C4)Cl)NS(=O)(=O)C
InChI
InChI=1S/C22H20ClN5O2S/c1-14(15-6-4-3-5-7-15)27-22-18-10-16(8-9-19(18)25-13-26-22)17-11-20(21(23)24-12-17)28-31(2,29)30/h3-14,28H,1-2H3,(H,25,26,27)/t14-/m1/s1
InChIKey
LPJIZDSOUGHTNB-CQSZACIVSA-N
Chemical Structure
2D Structure
2D structure of N-[(5P)-2-chloro-5-(4-{[(1R)-1-phenylethyl]amino}quinazolin-6-yl)pyridin-3-yl]methanesulfonamide
CAS: 2791417-66-6
CID: 164809124
Formula: C22H20ClN5O2S
MW: 453.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight453.9
XLogP34.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Exact Mass453.1026238
Monoisotopic Mass453.1026238
Topological Polar Surface Area105 Ų
Heavy Atom Count31
Formal Charge0
Complexity684
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19246626-01BM-531
GTR19029600-01AZP-531
GTR19231426-01KT-531
GTR19175218-01ARQ 531
GTR19174032-01HX 531
GTR19163524-01THZ 531
GTR19230852-01MTX-241F
GTR19220969-01MTX-23
GTR19236325-01MTX-3937
GTR19162905-01MTX-211

Alternative Products

CatalogName
E4680-100mgMTX-531
A24175-50MTX-531 50mg
A24175-100MTX-531 100mg
A24175-5MTX-531 5mg
A24175-10MTX-531 10mg
HY-156872MTX-216
T78877-01MTX-241F
B1968-25MTX-211
HY-148771-01MTX-23
T88712-01MTX-3937

Popular Products