PPARα agonist 5

CAT: 0013-GTR19258505-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19258505-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

PPARα agonist5 is an orally active, selective partial agonist of PPARα with an EC50 of 3 nM. It reduces lipid accumulation and upregulates PPARα target genes, exhibiting anti-hepatic steatosis properties. Additionally, PPARα agonist5 demonstrates significant lipid-lowering and glucose-lowering effects through partial PPARγ agonist activity and mild inhibition of protein tyrosine phosphatase 1B (PTP1B) with an IC50 of 79.1 μM. It has favorable safety and is applicable in the study of dyslipidemia in type 2 diabetes.

Field of Research

Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery

Storage Conditions

-20°C

Notes

For research use only.

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PPARα agonist 5

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