Products for Research Use Only

PPARδ agonist 11

CAT: 0013-GTR19238830-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238830-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Compound 11 is a potent and selective PPARδ agonist (EC50 = 20 nM) with demonstrated anti-inflammatory effects in vitro, suppressing NO, TNFα, and IL-6 via NF-κB in LPS-stimulated macrophages. It shows high metabolic stability, excellent oral bioavailability (~100%), and effectively reduces carrageenan-induced foot edema in vivo, making it a valuable tool for metabolic and inflammatory disease research.
CAS Number
2982696-04-6
Field of Research
Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery
Smiles
O=C (O) COC1=CC=C (SCC2=NN=C (S2) C=3C=CC (=CC3) C (F) (F) F) C=C1C
Molecular Formula
C19H15F3N2O3S2
Molecular Weight
440.46
Storage Conditions
-20°C
Notes
For research use only.