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DMT1 blocker 2

CAT: 0804-HY-126302-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0804-HY-126302-01Size:10 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DMT1 blocker 2 is a direct inhibitor of divalent metal transporter 1 (DMT1), with an IC50 of 0.83 μM. DMT1 blocker 2 can block iron uptake by enterocytes in vivo[1].
CAS Number
[1062648-63-8]
UNSPSC
12352005
Target
Ferroportin
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/dmt1-blocker-2.html
Purity
99.93
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC1=C2C3=C(C=CC=C3)CCC2=NN1C4=NC=CC=C4
Molecular Formula
C16H13N3O
Molecular Weight
263.29
References & Citations
[1]Cadieux JA, et, al. Synthesis and biological evaluation of substituted pyrazoles as blockers of divalent metal transporter 1 (DMT1) . Bioorg Med Chem Lett. 2012 Jan 1;22 (1) :90-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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