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(-) -KCC2 blocker 1

CAT: 0804-HY-18172B-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-18172B-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(-) -KCC2 blocker 1 is an enantiomer of KCC2 blocker 1. KCC2 blocker 1 (compound 13) is an orally active and selective K+-Cl- cotransporter KCC2 blocker with an IC50 of 1 μM[1].
CAS Number
1228439-73-3
UNSPSC
12352005
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Neurological Disease
Purity
99.19
Smiles
O=C(OCC1=CC=CC=C1)C2(CC3=CC=C(S(=O)(C)=O)C=C3)N(C(C)=O)CCC2
Molecular Formula
C22H25NO5S
Molecular Weight
415.50
References & Citations
[1]Pégurier C, et al. Benzyl prolinate derivatives as novel selective KCC2 blockers. Bioorg Med Chem Lett. 2010 Apr 15;20 (8) :2542-5.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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