Cav 2.2/3.2 blocker 1

• UNSPSC Description:

  Cav 2.2/3.2 blocker 1 (Compound 9e) is a neuronal calcium channel blocker with IC50 values of 78 μM and 80 μM against Cav2.2 and Cav3.2, respectively. Cav 2.2/3.2 blocker 1 can penetrate the CNS[1].

• Target Antigen:

  Calcium Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/cav-2-2-3-2-blocker-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1C2=CC=CC=C2CCC3=CC=CC=C31)C4=CC=C(OCCCN5CCOCC5)C=C4

• Molecular Weight:

  442.55

• References & Citations:

  [1]Cardoso FC, et al. The neuronal calcium ion channel activity of constrained analogues of MONIRO-1. Bioorg Med Chem. 2020 Sep 15;28(18):115655.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2987640-67-3