PROTAC SOS1 degrader-8

PROTAC SOS1 degrader-8

• CAS Number: 3036155-11-7
• UNSPSC Description: PROTAC SOS1 degrader-8 (Compd 1) is a PROTAC-based SOS1 degrader (Red: SOS1 Ligand (HY-161635), Black: linker (HY-W056267), Blue: E3 ligase ligand (HY-161637))[1].
• Target Antigen: PROTACs; Ras
• Type: Reference compound
• Related Pathways: GPCR/G Protein;MAPK/ERK Pathway;PROTAC
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-sos1-degrader-8.html
• Smiles: N#CC1=C(C)C([C@@H](C)NC2=NN=C(C)C3=C2C=C(N4CCN(C(C5CCN(CC6CCC7(CCN(C(C8=CC(N9CCC(NC9=O)=O)=C(Cl)C=C8)=O)CC7)CC6)CC5)=O)CC4)N=C3)=CC=C1
• Molecular Weight: 914.54
• References & Citations: [1]Zhengqing Ye, et al. Sos1 protein degradation agent and use thereof. Patent. WO2024083257A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported