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PROTAC SMARCA2 degrader-6

CAT: 0013-GTR19238955-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238955-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC SMARCA2 degrader-6 (I-427) is a potent and efficient small molecule that induces robust degradation of the SMARCA2 protein. It achieves a DC50 below 100 nM and over 90% degradation (Dmax) in A549 cells within 24 hours. This tool compound is valuable for probing SMARCA2 biology in cancer research and for preclinical in vitro mechanistic studies.
CAS Number
2568523-72-6
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
O=C (NCC=1C=CC (=CC1) C=2SC=NC2C) C3N (C (=O) C (NC (=O) C4CC5 (C4) CC (CN6CCC (C7=CN=C (N=C7) N8C9CN (C=%10C=C (N=NC%10N) C%11=CC=CC=C%11O) CC8CC9) CC6) C5) C (C) (C) C) CC (O) C3
Molecular Formula
C56H70N12O5S
Molecular Weight
1023.30
Storage Conditions
-20°C
Notes
For research use only.

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