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PROTAC SMARCA2 degrader-16

CAT: 0013-GTR19238750-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238750-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC SMARCA2 degrader-16 (I-278) is a potent and selective small molecule that induces robust degradation of the SMARCA2 protein, with a DC50 below 100 nM and >90% Dmax in A549 cells within 24 hours. This tool compound is valuable for probing SMARCA2 biology in oncology and targeted protein degradation research, both in vitro and in vivo.
CAS Number
2568276-37-7
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
O=C1NC (=O) C (N2C (=O) N (C3=CC (=CC=C32) CCCN4CCC (C5=NC=CC (=N5) N6C7CN (C=8C=C (N=NC8N) C9=CC=CC=C9O) CC6CC7) CC4) C) CC1
Molecular Formula
C41H47N11O4
Molecular Weight
757.88
Storage Conditions
-20°C
Notes
For research use only.

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