Products for Research Use Only

22-SLF

CAT: 0013-GTR19238318-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238318-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
22-SLF is a PROTAC molecule that induces FBXO22-dependent degradation of FKBP12 (DC50 = 0.5 μM) . It also demonstrates activity against other targets like BRD4 and the EML4-ALK fusion protein, making it a useful chemical probe for studying targeted protein degradation in cancer and disease models both in vitro and in vivo.
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Storage Conditions
-20°C
Notes
For research use only.