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EGFR-IN-22

CAT: 0013-GTR19221410-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19221410-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-22 is a potent small molecule inhibitor effective against both wild-type EGFR and the triple mutant EGFR L858R/T790M/C797S, with respective IC50 values of 4.91 nM and 0.54 nM. It serves as a valuable research tool for investigating resistance mechanisms and evaluating therapeutic strategies in preclinical in vitro and in vivo models of non-small cell lung cancer.
CAS Number
2634646-14-1
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
COc1cc (N2CCC3 (CC2) CCN (CC3) C (C) (C) CF) c (cc1Nc1ncc (Br) c (Nc2ccc3nccnc3c2P (C) (C) =O) n1) -c1cnn (C) c1
Molecular Formula
C38H47BrFN10O2P
Molecular Weight
805.72
Storage Conditions
-20°C
Notes
For research use only.

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