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SMARCA2-IN-8

CAT: 0013-GTR19238296-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238296-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SMARCA2-IN-8 (Compound 13) is a potent, orally bioavailable dual inhibitor of SMARCA2/BRM and SMARCA4/BRG1 with low nM IC50 values. It suppresses proliferation and target gene expression in SMARCA2-mutant cancer cells in vitro and demonstrates in vivo antitumor efficacy in mouse models, supporting its use in oncology research targeting SWI/SNF chromatin remodelers.
CAS Number
2270875-93-7
Field of Research
Neuroscience
Smiles
O=C (NC=1SN=C (C1) C (F) F) NC2=CC (F) =NC=C2N
Molecular Formula
C10H8F3N5OS
Molecular Weight
303.26
Storage Conditions
-20°C
Notes
For research use only.

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