SMARCA2-IN-6

CAT: 0931-MF-0142518-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0142518-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2270875-79-9
Target
Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Bioactivity
SMARCA2-IN-6 is a potent inhibitor of SMARCA2 (also known as BRM), exhibiting an IC50 of less than 5 nM against both SMARCA2 and SMARCA4. Additionally, this compound suppresses the expression of the KRT80 gene in H1299 cells with an IC50 of 26 nM and inhibits the proliferation of SKMEL5 cells carrying a BRG1 mutation with an IC50 value of 13 nM.
Smiles
O=C(NC=1SN=C(C1)C(F)F)NC2=CC(Cl)=NC=C2N
Molecular Formula
C10H8ClF2N5OS
Molecular Weight
319.72
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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HY-161885SMARCA2-IN-6
HY-159542SMARCA2 ligand-6
HY-171765SMARCA2/4-ligand-6
HY-159450PROTAC SMARCA2 degrader-6
HY-159457PROTAC SMARCA2/4-degrader-6
37955SMARCA2 Antibody
HY-161881SMARCA2-IN-9
HY-162740SMARCA2-IN-2
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HY-W494890SMARCA2-IN-10

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