SMARCA2-IN-4

• Bioactivity:

  SMARCA2-IN-4 (Compound 26) is an inhibitor of the SWI/SNF chromatin remodeling complex SMARCA, specifically targeting its bromodomain. This compound exhibits high affinity for PB1 (5), SMARCA2B, and SMARCA4, with dissociation constants (Kd) of 124, 262, and 417 nM, respectively.

• Smiles:

  C(=C\1/C=2N(C=3C(C(=O)N2)=C(Cl)C=CC3)CC1)\N4CCN(C)CC4

• Molecular Formula:

  C17H19ClN4O

• Molecular Weight:

  330.81

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1915012-19-9