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SMARCA2-IN-6

CAT: 0013-GTR19239006-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19239006-01Size:25 mg
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Description
SMARCA2-IN-6 is a potent, dual inhibitor of SMARCA2/BRM and SMARCA4/BRG1 with IC50 values below 5 nM. It downregulates KRT80 expression in H1299 cells (IC50=26 nM) and inhibits proliferation in BRG1-mutant SKMEL5 cells (IC50=13 nM), supporting its use in cancer research targeting SWI/SNF chromatin remodeling complexes.
CAS Number
2270875-79-9
Field of Research
Epigenetics & Chromatin, Neuroscience
Smiles
O=C (NC=1SN=C (C1) C (F) F) NC2=CC (Cl) =NC=C2N
Molecular Formula
C10H8ClF2N5OS
Molecular Weight
319.72
Storage Conditions
-20°C
Notes
For research use only.

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