Products for Research Use Only

SOS1-IN-16

CAT: 0013-GTR19218743-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19218743-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SOS1-IN-16 (Comp 54) is a potent and selective SOS1 inhibitor with an IC50 of 7.2 nM. It also inhibits CYP3A4 (IC50 = 8.9 μM with testosterone) . This compound is a valuable chemical probe for investigating SOS1/KRAS-dependent signaling pathways in cancer research, applicable in both cellular and biochemical studies.
CAS Number
2930763-85-0
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
N ([C@H] (C) C1=C (F) C (C (CO) (F) F) =CC=C1) C=2C3=C (C=CC (=C3) C4=CC (CC (N (C) C) =O) =C (OC) C=C4) N=C (C) N2
Molecular Formula
C30H31F3N4O3
Molecular Weight
552.59
Storage Conditions
-20°C
Notes
For research use only.